1) find a glitch in the game that gives my weapon either 4294967295 or 2147483647 damage, assuming the developers are using a 4 byte integer for weapon damage.
2) try to kill everyone with that weapon
3) start cursing when #2 fails
4) try to kill an npc
5) curse even more when that npc kills me

wait a second....if a weapon did 4294967295 damage plus damage from char stats that would mean the number would roll over and only do stat damage.
DO\'H
in that case i\'ll just take a weapon that does 1 mil damage.