Most things are shipped in contained envirenments ~60 degrees F. so unless they just set it on your doorstep, it should never get too cold. Not that it would hurt it. In fact, electronic equipment generally work better when cold. It makes things more conductive. As for dead pixels, I have never had one on a LCD screen. I dont know how often they happen, but I don\'t worry about them. I did however have one on my old CRT monitor. But I never noticed it. I don\'t even know how long it was there before I finally did notice it. If the screen you buy has an insanly high resolution, it will be so small it wont affect anything. The only time you really notice them is when the screen is displaying something very bright.