I don't understand why having that specific directional reference or not drives people to such bitterness. I really don't mind either way if we have north, south, east, west or something else. Just when travel on a level is along a curve, a system that's usually thought about in terms of straight lines isn't so great to my thinking. Either way, not my choice and I don't see a point in being negative about it one way or another.
What would be great is a way for NPCs to offer more in terms of directions toward things if asked. Apparently north, south, east, west were decided unacceptable long before I ever showed up on the scene. I'm not going to apologise for daring to consider an alternative. I'm not really a fan of making directions unreasonably different either since they should be accessible to new players, but not having a compass was never up to me. I'd say the ones riding dead horses here are those who only moan instead of trying to be constructive.
Point being - Compass points or not, it should be possible to get NPCs to direct players better than they currently do. Be that in terms of answers to things like "Where does this road go?" or "How do I reach Gugrontid?" ("Follow the path through this gate until you see/pass xxx, then watch out for xxx, but you might want to think of asking someone to show you the way the first time, or taking the pterosaur if you don't know how to get there.")
Or directions in another sense, like Denes has pointed out so well. NPC responses can help a player learn so much about the game. Currency. Food. The different races. What wild creatures to expect. (If a guard is guarding a gate, he should know what from, maybe?)